Michael Hothorn

Labs 1078 - 1081
+41 22 379 30 13

Structural Plant Biology


» Lab website


Research Interests

  • Plant membrane signal transduction
  • Inositol pyrophosphate and inorganic polyphosphate metabolism and signaling


Key Publications

Okuda S., Fujita S., Moretti A., Hohmann U., Doblas V.G., Ma Y., Pfister A., Brandt B., Geldner N. & Hothorn M.:
Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2.
Proc Natl Acad Sci U S A 2020, 117(5):2693-2703. PMID: 31964818.

Zhu J., Lau K., Puschmann R., Harmel R.K., Zhang Y., Pries V., Gaugler P., Broger L., Dutta A.K., Jessen H.J., Schaaf G., Fernie A.R., Hothorn L.A., Fiedler D. & Hothorn M.:
Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis.
Elife 2019, 8. PMID: 31436531.

Lau K., Podolec R., Chappuis R., Ulm R. & Hothorn M.:
Plant photoreceptors and their signaling components compete for COP1 binding via VP peptide motifs.
EMBO J 2019, 38(18):e102140. PMID: 31304983.

Lorenzo-Orts L., Witthoeft J., Deforges J., Martinez J., Loubéry S., Placzek A., Poirier Y., Hothorn L.A., Jaillais Y. & Hothorn M.:
Concerted expression of a cell cycle regulator and a metabolic enzyme from a bicistronic transcript in plants.
Nat Plants 2019, 5(2):184-193. PMID: 30737513.

Hohmann U., Santiago J., Nicolet J., Olsson V., Spiga F.M., Hothorn L.A., Butenko M.A. & Hothorn M.:
Mechanistic basis for the activation of plant membrane receptor kinases by SERK-family coreceptors.
Proc Natl Acad Sci U S A 2018, 115(13):3488-3493. PMID: 29531026.


Further Reading

Lorenzo-Orts L., Couto D. & Hothorn M.:
Identity and functions of inorganic and inositol polyphosphates in plants.
New Phytol 2020, 225(2):637-652. PMID: 31423587.

Hohmann U., Lau K. & Hothorn M.:
The Structural Basis of Ligand Perception and Signal Activation by Receptor Kinases.
Annu Rev Plant Biol 2017, 68:109-137. PMID: 28125280.





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